Vascular dysfunction is an early feature of diabetic vascular disease, due to increased oxidative stress and reduced nitric oxide (NO) bioavailability.This Vacuum Motor can lead to endothelial cell senescence and clinical complications such as stroke.Cells can become senescent by shortened telomeres and oxidative stress is known to accelerate telom
Abstract While the physiological and transcriptional response of the host to biotic and abiotic stresses have been intensely studied, little is known about the resilience of associated microbiomes and their contribution towards tolerance or response to these stresses.We evaluated the impact of elevated tropospheric ozone (O3), individually and in c
IntroductionOver the past few years, several studies have described the brain activation pattern related to both time discrimination (TD) and change detection processes.We hypothesize that both processes share a common brain network which may play a significant role in more complex cognitive processes.The main goal of this proof-of-concept study is
Abstract Background Scimitar syndrome is a rare form of partial anomalous pulmonary venous drainage associated with pulmonary hypertension and congestive heart failure that may lead to death in the newborn COENZYME Q10 LIP BALM infant.Although it is described with anomalies of the lung, heart and their vascular structure, extremely rare association
Abstract Background The offspring of consanguineous relations have an increased risk of congenital/genetic disorders and early mortality.Consanguineous couples and their offspring account for approximately 10% of the global population.The increased risk for congenital/genetic disorders is most marked for autosomal recessive disorders and depends on